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Tracker

Biotech winners and losers

The biotech stocks with the biggest reported moves, up and down, and the news behind each one: takeovers, trial results, IPO debuts and financings.

Moves as reported on the dates shown, as of October 23, 2026. Each line comes from a fact-checked story or the company's own release. All trackers.

Biggest gainers

DateCompanyMoveWhy
Oct 19Silence Therapeutics SLN+130%Merck KGaA offers $20 per ADS in cash, a 130% premium to the Oct. 16 close. Our story
Oct 16City Therapeutics CTY+28%Opened at $23 on its Nasdaq debut after an upsized $200 million IPO priced at $18. Our story
Oct 20Disc Medicine IRON$450MUpsized raise at $75 a share, one day after a positive phase 3 result. Our story
Oct 9Vaxcyte PCVX$1.1BRaised about $1.1 billion at $64 a share and a 1.50% convertible, after a phase 3 win. Our story
Sep 24Viking Therapeutics VKTX+45%Sold $259 million of 2% converts at a 45% conversion premium, plus stock at $35, after maintenance data. Our story
Aktis Oncology AKTSIPO upsized, raises about $318M at $18 Our story
Alumis ALMSRaises $300M after psoriasis pill wins phase 3 Our story
Monte Rosa Therapeutics GLUEUpsizes stock sale to $300M after NEK7 data Our story
United Therapeutics UTHRAuthorizes another $2B share buyback Our story
Ultragenyx RARESells two priority review vouchers for $413M Our story
Protagonist Therapeutics PTGX$300M buyback after two drug approvals Our story
Celldex Therapeutics CLDXCloses $345M raise, funded through 2028 Our story

Biggest losers

DateCompanyMoveWhy
Oct 19EyePoint EYPT-80%Shares fell more than 80% at the open to 55 cents after a second Duravyu wet AMD phase 3 miss. Our story
Oct 16Fractyl Health GUTS-48%Shares fell about 48% to around $2.14 even though Revita met its six-month endpoint. Our story
Aug 31BioAtla BCABOTCNasdaq upheld its delisting. Trading moved from Nasdaq to the OTC Markets under BCAB on Aug. 31. SEC Form 8-K
Sep 19Xenon XENE-26%Shares fell 26% pre-market to $42.25 from $57.35 after it paused phase 3 depression enrollment. Our story
Oct 21Arcus Biosciences RCUS-8%Raised $250 million at $17.50, about 8% below the last sale, after the stock fell about 20% in two days. Our story
BioXcel Therapeutics BTAIFiles Chapter 11, Teva is stalking horse Our story
TScan Therapeutics TCRXCuts 75% of staff, pauses phase 3 Our story
Lisata Therapeutics LSTACuts 72% of staff after failed buyout Our story
Sangamo Therapeutics SGMONasdaq delisting final in Chapter 11 Our story
Senti Biosciences SNTITwo Nasdaq notices: bid price and equity Our story
Capricor Therapeutics CAPRNew class action and derivative suit Our story
Outlook Therapeutics OTLKNasdaq bid-price notice after approval Our story

Reported moves, not a recommendation to buy or sell. How we work.

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