aibioRFL Rafael Holdings, Inc.
Rafael Holdings (RFL) news
Rafael Holdings, Inc. is a public biotech or pharmaceutical company listed on NYSE under the ticker RFL, recorded under United States. aibio.space tracks 2,820 public biotech companies worldwide and publishes investor news on them.
Latest Rafael Holdings news
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What Rafael Holdings does
Rafael Holdings is a biotechnology company that develops pharmaceuticals and holds interests in clinical and early-stage companies developing pharmaceuticals and medical devices. Its lead candidate, Trappsol Cyclo (remibetadex), is an investigational therapy for Niemann-Pick Disease Type C, a rare, fatal and progressive genetic disorder. The company says it has completed the pivotal Phase 3 trial and submitted a New Drug Application to the FDA on October 28, 2026. The Phase 3 study did not meet its primary endpoint in the overall population, while a prespecified analysis in patients receiving background miglustat and/or leucine therapy showed a statistically significant treatment benefit. Its subsidiary Cyclo became wholly owned through a merger completed March 25, 2025. Other holdings include LipoMedix, a clinical-stage company developing Promitil, a liposome-based cancer candidate; Barer Institute, which holds early-stage cancer assets; Cornerstone Pharmaceuticals, a cancer metabolism-based therapeutics company; Rafael Medical Devices, an orthopedic-focused device company; and Day Three Labs, which provides technology to third-party manufacturers.
| Product or program | What it is | Stage |
|---|---|---|
| Trappsol Cyclo (remibetadex) | Investigational therapy for Niemann-Pick Disease Type C | pivotal Phase 3 completed; NDA submitted October 28, 2026 |
| Promitil | Liposome-delivery candidate for cancer, developed by LipoMedix | clinical stage |
Rafael Holdings annual financials
| Line | FY ended Jul 31, 2026 | FY ended Jul 31, 2025 |
|---|---|---|
| Revenue | $917,000 | |
| Research and development | $24.3 million | $12.8 million |
| Net income (loss) | -$29.6 million | -$30.5 million |
| Cash from operations | -$30.0 million | -$18.9 million |
| Cash and equivalents | $22.1 million | $52.8 million |
Questions about Rafael Holdings
What is the ticker symbol of Rafael Holdings?
Rafael Holdings, Inc. trades under the ticker RFL on NYSE.
Where is Rafael Holdings listed?
Rafael Holdings, Inc. is listed on NYSE.
Which country or territory is Rafael Holdings listed under?
Our directory records Rafael Holdings, Inc. under United States.
Does aibio.space cover Rafael Holdings?
aibio.space lists Rafael Holdings, Inc. among 2,820 public biotech companies and publishes its news here as stories appear.
What does Rafael Holdings develop?
Rafael Holdings is a biotechnology company that develops pharmaceuticals and holds interests in clinical and early-stage companies developing pharmaceuticals and medical devices. Its lead candidate, Trappsol Cyclo (remibetadex), is an investigational therapy for Niemann-Pick Disease Type C, a rare, fatal and progressive genetic disorder.
What is Trappsol Cyclo (remibetadex) from Rafael Holdings?
Trappsol Cyclo (remibetadex): Investigational therapy for Niemann-Pick Disease Type C Stage: pivotal Phase 3 completed; NDA submitted October 28, 2026.
What is Promitil from Rafael Holdings?
Promitil: Liposome-delivery candidate for cancer, developed by LipoMedix Stage: clinical stage.
Is Rafael Holdings profitable?
Rafael Holdings, Inc. reported a net loss of $29.6 million for the fiscal year ended Jul 31, 2026, and used $30.0 million of cash in operations, per its annual report to the SEC.
How much does Rafael Holdings spend on research and development?
$24.3 million in the fiscal year ended Jul 31, 2026, per its annual report.
How much cash does Rafael Holdings have?
$22.1 million in cash at Jul 31, 2026, per its 10-K.
Investor discussion: Rafael Holdings
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Reported substantial doubt about its ability to continue as a going concern. SEC Form 10-K. Source
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- Rafael Holdings, Inc.
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- RFL
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- United States
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