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IONS Ionis Pharmaceuticals, Inc. NASDAQ · United States

Ionis Pharmaceuticals (IONS) news

Top story · Oct 23, 2026 · SEC filing 8-K

Ionis Pharmaceuticals files a company update

On October 23, 2026, Ionis’ partner, Roche, announced late-breaking oral presentation data from the ongoing Phase 3 IMAgINATION study in adults with primary IgAN receiving optimized standard of care, demonstrating that investigational sefaxersen achieved a statistically significant and clinically meaningful 43.1% reduction in proteinuria (95% confidence interval [CI]: 32.5 - 52.0, P The treatment effect

Source: 8-K filed Oct 23, 2026 on SEC EDGAR

Latest Ionis Pharmaceuticals news

We have not published a story on Ionis Pharmaceuticals yet. When there is news, it will appear here.

Ionis Pharmaceuticals annual financials

LineFY2025FY2024
Research and development$915.6 million$901.5 million
Net income (loss)-$381.4 million-$453.9 million
Cash from operations-$268.6 million-$500.9 million
Cash and equivalents$372.3 million$242.1 million
Short-term investments$2.31 billion$2.06 billion

Latest balance sheet, Jun 30, 2026 (10-Q): cash and equivalents $350.1 million, plus short-term investments of $1.70 billion, $2.05 billion in all.

Figures as reported to the SEC in XBRL; each one links to its filing. Not adjusted, not investment advice.

Questions about Ionis Pharmaceuticals

What is the ticker symbol of Ionis Pharmaceuticals?

Ionis Pharmaceuticals, Inc. trades under the ticker IONS on NASDAQ.

Where is Ionis Pharmaceuticals listed?

Ionis Pharmaceuticals, Inc. is listed on NASDAQ. Our directory also records these other listings: DUS:ISI; FWB:ISI; GETTEX:ISI; HAM:ISI; HAN:ISI; LS:A2ACMZ; LSE:0JDI; LSX:A2ACMZ; MUN:ISI; SWB:ISI; TRADEGATE:ISI; XETR:ISI.

What is the SEC CIK of Ionis Pharmaceuticals?

The SEC Central Index Key (CIK) for Ionis Pharmaceuticals, Inc. is 874015. Its filings are on SEC EDGAR.

How many shares does Ionis Pharmaceuticals have outstanding?

166,184,322 shares as of 2026-07-23, per the cover page of its 10-Q filed 2026-07-29.

Which country or territory is Ionis Pharmaceuticals listed under?

Our directory records Ionis Pharmaceuticals, Inc. under United States.

What does Ionis Pharmaceuticals do?

Our directory classifies Ionis Pharmaceuticals, Inc. as: Pharmaceuticals: Major. This is a directory classification, not a description of the pipeline.

What is the ISIN of Ionis Pharmaceuticals?

The ISIN recorded for Ionis Pharmaceuticals, Inc. is US4622221004.

Does aibio.space cover Ionis Pharmaceuticals?

aibio.space lists Ionis Pharmaceuticals, Inc. among 2,820 public biotech companies and publishes its news here as stories appear.

Where is Ionis Pharmaceuticals incorporated?

SEC records list its state or country of incorporation as CA.

Is Ionis Pharmaceuticals profitable?

Ionis Pharmaceuticals, Inc. reported a net loss of $381.4 million for the fiscal year ended Dec 31, 2025, and used $268.6 million of cash in operations, per its annual report to the SEC.

How much does Ionis Pharmaceuticals spend on research and development?

$915.6 million in the fiscal year ended Dec 31, 2025, per its annual report.

How much cash does Ionis Pharmaceuticals have?

$2.05 billion in cash and short-term investments at Jun 30, 2026, per its 10-Q.

What is Ionis Pharmaceuticals's market cap?

We do not publish live share prices. In its annual report, Ionis Pharmaceuticals, Inc. put the market value of shares held by non-affiliates (public float) at $5.28 billion as of Jun 30, 2025.

Is Ionis Pharmaceuticals a smaller reporting company?

SEC records list Ionis Pharmaceuticals, Inc.'s filer category as: Large accelerated filer.

Where is Ionis Pharmaceuticals headquartered?

SEC records list its business address as 2855 GAZELLE COURT, CARLSBAD, CA, 92010.

Investor discussion: Ionis Pharmaceuticals

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Capital-markets timeline

Financings, listing notices, splits, legal actions and other investor events at Ionis Pharmaceuticals, newest first. Each line links the filing it comes from.

  1. Financings

    Reported a financing. SEC Form 8-K (Items 1.01,2.03,3.02,8.01,9.01). Source

Stock chart

Price chart and quote supplied by TradingView, delayed as the exchange requires. It loads only if you choose to show it. Information only, not investment advice. Open NASDAQ:IONS on TradingView.

SEC filings and registration

SEC name
Ionis Pharmaceuticals Inc
CIK
874015
Industry (SIC)
Pharmaceutical Preparations (2834)
US tickers
IONS (Nasdaq)
State or country of incorporation
CA
Fiscal year ends
December 31
Filer category
Large accelerated filer
Business address
2855 GAZELLE COURT, CARLSBAD, CA, 92010
Phone
7609319200
Shares outstanding
166,184,322 as of 2026-07-23 (10-Q filed 2026-07-29)
Former names
ISIS PHARMACEUTICALS INC

Recent filings (8-K and 6-K are the company's own announcements)

  • 8-K filed 2026-10-21
  • 8-K filed 2026-09-23
  • 8-K filed 2026-09-04
  • 8-K filed 2026-09-04
  • 10-Q filed 2026-07-29
  • 8-K filed 2026-07-29
  • 8-K filed 2026-07-10
  • 8-K filed 2026-07-09

Source: SEC EDGAR, retrieved October 23, 2026. Shares outstanding is the cover-page figure from the latest periodic report. The SEC does not publish share prices.

Listing details

Ionis Pharmaceuticals, Inc. is a public biotech or pharmaceutical company listed on NASDAQ under the ticker IONS, recorded under United States. The directory classifies it as Pharmaceuticals: Major. aibio.space tracks 2,820 public biotech companies worldwide and publishes investor news on them.

Company
Ionis Pharmaceuticals, Inc.
Ticker
IONS
Listing
NASDAQ
Country or territory
United States
Business scope
Pharmaceuticals: Major
ISIN
US4622221004
Other listed symbols
DUS:ISI; FWB:ISI; GETTEX:ISI; HAM:ISI; HAN:ISI; LS:A2ACMZ; LSE:0JDI; LSX:A2ACMZ; MUN:ISI; SWB:ISI; TRADEGATE:ISI; XETR:ISI
Last quote in directory
2026-10-21
Directory source
Listing page

Listing facts come from our company directory, researched on October 22, 2026. A listing record does not certify that a security currently trades. Tell us about a change. Work at this company? Claim this page.

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Who manages this page This page is managed by aibio.space. The company does not run, edit or pay for this page. News, desk views and Investor Ranks are written and managed independently by aibio.space under our editorial and analytical judgment. Opinion only, not investment advice. How we work · Terms · Request a correction

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