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GHRS GH Research PLC NASDAQ · Ireland

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Latest GH Research news

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What GH Research does

GH Research PLC is a clinical-stage biopharmaceutical company developing treatments for depression, with an initial focus on treatment-resistant depression, or TRD. Its lead candidate, GH001, is an inhalable mebufotenin product, and its second candidate, GH002, is an intravenous mebufotenin product. GH001 has completed two Phase 1 healthy volunteer trials, a Phase 1/2 trial in patients with TRD, and a randomized, double-blind, placebo-controlled Phase 2b trial with an open-label extension. The company is developing a proprietary aerosol delivery device with a contract development and manufacturing organization for a pivotal program it expects to start in 2026. The FDA placed the GH001 IND on clinical hold in 2023, and the hold was lifted in December 2025 after the company submitted a complete response in November 2025. The company estimates there are approximately nine million TRD patients in the United States and Europe, and it notes that the two approved pharmacotherapies for TRD have mixed efficacy and potential side effects. GH Research was incorporated in Ireland in 2021 as a holding company for GH Research Ireland Limited.

Product or programWhat it isStage
GH001Inhalable mebufotenin for treatment-resistant depressionPhase 2b completed; pivotal trial expected to start in 2026
GH002Intravenous mebufotenin candidate for psychiatric and neurological disordersdose-ranging clinical pharmacology trial completed in healthy volunteers

Summarised from the company's 20-F filed Mar 5, 2026.

GH Research annual financials

LineFY2025FY2024
Research and development$38.8 million$35.0 million
Net income (loss)-$48.3 million-$39.0 million
Cash from operations-$43.6 million-$42.3 million
Cash and equivalents$246.3 million$100.8 million
Short-term investments$0$19.4 million

Latest balance sheet, Dec 31, 2025 (20-F): cash and equivalents $246.3 million, plus short-term investments of $0, $246.3 million in all.

Figures as reported to the SEC in XBRL; each one links to its filing. Not adjusted, not investment advice.

Questions about GH Research

Has GH Research raised money recently?

Our latest story on this, dated Aug 6, 2026: "GH Research reports $111.2 million net proceeds from April 2026 share offering". The story links the filing or release it is based on. Read the story.

What is the ticker symbol of GH Research?

GH Research PLC trades under the ticker GHRS on NASDAQ.

Where is GH Research listed?

GH Research PLC is listed on NASDAQ. Our directory also records these other listings: GETTEX:1KA; LS:A3CUAZ; LSX:A3CUAZ.

What is the SEC CIK of GH Research?

The SEC Central Index Key (CIK) for GH Research PLC is 1855129. Its filings are on SEC EDGAR.

How many shares does GH Research have outstanding?

62,029,395 shares as of 2025-12-31, per the cover page of its 20-F filed 2026-03-05.

Which country or territory is GH Research listed under?

Our directory records GH Research PLC under Ireland.

What does GH Research do?

Our directory classifies GH Research PLC as: Biopharma / pharmaceutical profile checked. This is a directory classification, not a description of the pipeline.

What is the ISIN of GH Research?

The ISIN recorded for GH Research PLC is IE000GID8VI0.

Does aibio.space cover GH Research?

aibio.space lists GH Research PLC among 2,820 public biotech companies and publishes its news here as stories appear.

Where is GH Research incorporated?

SEC records list its state or country of incorporation as L2.

What does GH Research develop?

GH Research PLC is a clinical-stage biopharmaceutical company developing treatments for depression, with an initial focus on treatment-resistant depression, or TRD. Its lead candidate, GH001, is an inhalable mebufotenin product, and its second candidate, GH002, is an intravenous mebufotenin product.

What is GH001 from GH Research?

GH001: Inhalable mebufotenin for treatment-resistant depression Stage: Phase 2b completed; pivotal trial expected to start in 2026.

What is GH002 from GH Research?

GH002: Intravenous mebufotenin candidate for psychiatric and neurological disorders Stage: dose-ranging clinical pharmacology trial completed in healthy volunteers.

Is GH Research profitable?

GH Research PLC reported a net loss of $48.3 million for the fiscal year ended Dec 31, 2025, and used $43.6 million of cash in operations, per its annual report to the SEC.

How much does GH Research spend on research and development?

$38.8 million in the fiscal year ended Dec 31, 2025, per its annual report.

Investor discussion: GH Research

Members talk about GH Research (GHRS). Reader posts, not aibio.space reporting, and not investment advice.

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Capital-markets timeline

Financings, listing notices, splits, legal actions and other investor events at GH Research, newest first. Each line links the filing it comes from.

  1. Financings

    Reported a financing. SEC Form 6-K. Source

  2. Financings

    Reported a financing. SEC Form 424B5. Source

  3. Financings

    Reported a financing. SEC Form 424B5. Source

  4. Financings

    Reported a financing. SEC Form 6-K. Source

Stock chart

Price chart and quote supplied by TradingView, delayed as the exchange requires. It loads only if you choose to show it. Information only, not investment advice. Open NASDAQ:GHRS on TradingView.

SEC filings and registration

SEC name
GH Research PLC
CIK
1855129
Industry (SIC)
Pharmaceutical Preparations (2834)
US tickers
GHRS (Nasdaq)
State or country of incorporation
L2
Fiscal year ends
December 31
Filer category
Accelerated filer<br>Emerging growth company
Business address
JOSHUA DAWSON HOUSE, DUBLIN 2, Ireland, D02 RY95
Phone
353 1 437 8334
Shares outstanding
62,029,395 as of 2025-12-31 (20-F filed 2026-03-05)

Recent filings (8-K and 6-K are the company's own announcements)

  • 6-K filed 2026-10-09
  • 6-K filed 2026-09-11
  • 6-K filed 2026-08-06
  • 6-K filed 2026-06-26
  • 6-K filed 2026-06-04
  • 6-K filed 2026-05-21
  • 6-K filed 2026-05-14
  • 424B5 filed 2026-05-14

Source: SEC EDGAR, retrieved October 23, 2026. Shares outstanding is the cover-page figure from the latest periodic report. The SEC does not publish share prices.

Listing details

GH Research PLC is a public biotech or pharmaceutical company listed on NASDAQ under the ticker GHRS, recorded under Ireland. The directory classifies it as Biopharma / pharmaceutical profile checked. aibio.space tracks 2,820 public biotech companies worldwide and publishes investor news on them.

Company
GH Research PLC
Ticker
GHRS
Listing
NASDAQ
Country or territory
Ireland
Business scope
Biopharma / pharmaceutical profile checked
ISIN
IE000GID8VI0
Other listed symbols
GETTEX:1KA; LS:A3CUAZ; LSX:A3CUAZ
Last quote in directory
2026-10-21
Directory source
Listing page

Listing facts come from our company directory, researched on October 22, 2026. A listing record does not certify that a security currently trades. Tell us about a change. Work at this company? Claim this page.

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Who manages this page This page is managed by aibio.space. The company does not run, edit or pay for this page. News, desk views and Investor Ranks are written and managed independently by aibio.space under our editorial and analytical judgment. Opinion only, not investment advice. How we work · Terms · Request a correction

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