---
title: "Rafael Holdings (RFL) stock: news and investor profile"
url: "https://aibio.space/companies/rafael/"
publisher: "aibio.space (Biotech Investor Relations News)"
summary: "Rafael Holdings, Inc. (NYSE: RFL), United States. Listing facts, related biotech companies and news on aibio.space."
---

RFL Rafael Holdings, Inc. NYSE · United States

# Rafael Holdings (RFL) news

Rafael Holdings, Inc. is a public biotech or pharmaceutical company listed on NYSE under the ticker RFL, recorded under United States. aibio.space tracks 2,820 public biotech companies worldwide and publishes investor news on them.

## Latest Rafael Holdings news

We have not published a story on Rafael Holdings yet. When there is news, it will appear here.

## Rafael Holdings at a glance

- **Ticker**: RFL

- **Listing**: NYSE

- **Country**: United States

- **Cash, Jul 31, 2026**: $22.1 million

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## What Rafael Holdings does

Rafael Holdings is a biotechnology company that develops pharmaceuticals and holds interests in clinical and early-stage companies developing pharmaceuticals and medical devices. Its lead candidate, Trappsol Cyclo (remibetadex), is an investigational therapy for Niemann-Pick Disease Type C, a rare, fatal and progressive genetic disorder. The company says it has completed the pivotal Phase 3 trial and submitted a New Drug Application to the FDA on October 28, 2026. The Phase 3 study did not meet its primary endpoint in the overall population, while a prespecified analysis in patients receiving background miglustat and/or leucine therapy showed a statistically significant treatment benefit. Its subsidiary Cyclo became wholly owned through a merger completed March 25, 2025. Other holdings include LipoMedix, a clinical-stage company developing Promitil, a liposome-based cancer candidate; Barer Institute, which holds early-stage cancer assets; Cornerstone Pharmaceuticals, a cancer metabolism-based therapeutics company; Rafael Medical Devices, an orthopedic-focused device company; and Day Three Labs, which provides technology to third-party manufacturers.

| Product or program | What it is | Stage |
|---|---|---|
| Trappsol Cyclo (remibetadex) | Investigational therapy for Niemann-Pick Disease Type C | pivotal Phase 3 completed; NDA submitted October 28, 2026 |
| Promitil | Liposome-delivery candidate for cancer, developed by LipoMedix | clinical stage |

Summarised from the company's [10-K filed Oct 29, 2026](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/ea0309115-10k_rafael.htm).

## Rafael Holdings annual financials

| Line | FY ended Jul 31, 2026 | FY ended Jul 31, 2025 |
|---|---|---|
| Revenue |  | [$917,000](https://www.sec.gov/Archives/edgar/data/1713863/000121390025103549/) |
| Research and development | [$24.3 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/) | [$12.8 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/) |
| Net income (loss) | [-$29.6 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/) | [-$30.5 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/) |
| Cash from operations | [-$30.0 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/) | [-$18.9 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/) |
| Cash and equivalents | [$22.1 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/) | [$52.8 million](https://www.sec.gov/Archives/edgar/data/1713863/000121390026067560/) |

Latest balance sheet, Jul 31, 2026 (10-K): cash and equivalents $22.1 million.

Figures as reported to the SEC in XBRL; each one links to its filing. Not adjusted, not investment advice.

## Questions about Rafael Holdings

What is the ticker symbol of Rafael Holdings?

Rafael Holdings, Inc. trades under the ticker RFL on NYSE.

Where is Rafael Holdings listed?

Rafael Holdings, Inc. is listed on NYSE.

Which country or territory is Rafael Holdings listed under?

Our directory records Rafael Holdings, Inc. under United States.

Does aibio.space cover Rafael Holdings?

aibio.space lists Rafael Holdings, Inc. among 2,820 public biotech companies and publishes its news here as stories appear.

What does Rafael Holdings develop?

Rafael Holdings is a biotechnology company that develops pharmaceuticals and holds interests in clinical and early-stage companies developing pharmaceuticals and medical devices. Its lead candidate, Trappsol Cyclo (remibetadex), is an investigational therapy for Niemann-Pick Disease Type C, a rare, fatal and progressive genetic disorder.

What is Trappsol Cyclo (remibetadex) from Rafael Holdings?

Trappsol Cyclo (remibetadex): Investigational therapy for Niemann-Pick Disease Type C Stage: pivotal Phase 3 completed; NDA submitted October 28, 2026.

What is Promitil from Rafael Holdings?

Promitil: Liposome-delivery candidate for cancer, developed by LipoMedix Stage: clinical stage.

Is Rafael Holdings profitable?

Rafael Holdings, Inc. reported a net loss of $29.6 million for the fiscal year ended Jul 31, 2026, and used $30.0 million of cash in operations, per its annual report to the SEC.

How much does Rafael Holdings spend on research and development?

$24.3 million in the fiscal year ended Jul 31, 2026, per its annual report.

How much cash does Rafael Holdings have?

$22.1 million in cash at Jul 31, 2026, per its 10-K.

## Investor discussion: Rafael Holdings

Members talk about Rafael Holdings (RFL). Reader posts, not aibio.space reporting, and not investment advice.

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## Capital-markets timeline

Financings, listing notices, splits, legal actions and other investor events at Rafael Holdings, newest first. Each line links the filing it comes from.

1. 2026-10-29 Distress Reported substantial doubt about its ability to continue as a going concern. SEC Form 10-K. [Source](https://www.sec.gov/Archives/edgar/data/1713863/000121390026113659/ea0309115-10k_rafael.htm)

## Stock chart

Price chart and quote supplied by TradingView, delayed as the exchange requires. It loads only if you choose to show it. Information only, not investment advice. [Open NYSE:RFL on TradingView](https://www.tradingview.com/symbols/NYSE-RFL/).

## Listing details

Rafael Holdings, Inc. is a public biotech or pharmaceutical company listed on NYSE under the ticker RFL, recorded under United States. aibio.space tracks 2,820 public biotech companies worldwide and publishes investor news on them.

- **Company**: Rafael Holdings, Inc.

- **Ticker**: RFL

- **Listing**: NYSE

- **Country or territory**: United States

Listing facts come from our company directory, researched on October 22, 2026. A listing record does not certify that a security currently trades. [Tell us about a change](https://aibio.space/reputation/#update). Work at this company? [Claim this page](https://aibio.space/claim/).

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Source page: https://aibio.space/companies/rafael/. Facts in aibio.space stories are checked against company filings and releases; opinion is labelled. Cite as: aibio.space, "Rafael Holdings (RFL) stock: news and investor profile", 2026-10-31, https://aibio.space/companies/rafael/
