--- title: "IDEAYA Biosciences (IDYA): news, pipeline and catalysts" url: "https://aibio.space/companies/ideaya-biosciences/" publisher: "aibio.space (Biotech Investor Relations News)" summary: "IDEAYA Biosciences news for investors: IDEAYA Biosciences is a South San Francisco precision oncology company developing targeted cancer drugs, led by…" --- Desk view · Opinion · Updated Oct 22, 2026 ## IDEAYA's eye cancer drug is near the market. The pipeline must do the rest IDEAYA has a drug with positive randomized data, a filing in progress and more than $1.2 billion in the bank. The approval case looks sound; the commercial ceiling in uveal melanoma is the limit. Whether IDE849 and the MTAP programs work will decide how big the company can get. Read the full desk view aibio.space Investor Rank · Opinion **9** /10 Most positive view Darovasertib won a randomized trial, a filing is under way and cash runs into 2030; the small uveal melanoma market limits growth without the pipeline. - **Technology**: 2/2 - **Odds**: 2/2 - **Balance sheet**: 2/2 - **Risk**: 1/2 - **Momentum**: 2/2 Opinion only. The Investor Rank is aibio.space's opinion of the company's business position, drawn from the public sources on this page. It is not a recommendation to buy, sell or hold any security and it is not investment advice. It does not consider the share price, valuation or your circumstances, and it can change at any time. Payments from companies never affect it. [How the rank works](https://aibio.space/disclosures/#rank). - **Technology**: **Validated in a randomized trial.** Darovasertib plus crizotinib cut the risk of progression or death by 58% (hazard ratio 0.42) in OptimUM-02. - **Odds**: **High for the lead drug.** The NDA is due to be completed in the second half of 2026, and 90.6% of filed drugs win approval historically. - **Balance sheet**: **Strong.** About $1.24 billion at June 30, 2026 after a $323.4 million net raise, with runway into 2030. - **Main risk**: **Small market.** GlobalData forecasts $709 million of darovasertib sales by 2032, so growth needs earlier settings or the pipeline. - **Watch next**: **Filing and first ADC data.** IDEAYA expects to complete the NDA and report its own IDE849 data in the second half of 2026. ## Top news on IDEAYA ## Dates **October 24, 2026** ESMO poster presentations of OptimUM-01, OptimUM-02 subgroup and OptimUM-09 data [Source](https://ir.ideayabio.com/2026-10-19-IDEAYA-Biosciences-and-Servier-Announce-Data-From-Three-Clinical-Trials-at-ESMO-2026-Supporting-the-Potential-of-Darovasertib-to-Become-a-Foundational-New-Therapy-for-Patients-Across-the-Treatment-Journey-of-Uveal-Melanoma) **November 16, 2026** Investor R&D day in London on MTAP/CDKN2A and KRAS strategy in pancreatic cancer [Source](https://ir.ideayabio.com/2026-09-01-IDEAYA-Biosciences-Announces-London-Investor-R-D-Day-and-Participation-in-Upcoming-September-2026-Investor-Conferences) **Second half of 2026** Completion of darovasertib NDA submission [Source](https://ir.ideayabio.com/2026-10-19-IDEAYA-Biosciences-and-Servier-Announce-Data-From-Three-Clinical-Trials-at-ESMO-2026-Supporting-the-Potential-of-Darovasertib-to-Become-a-Foundational-New-Therapy-for-Patients-Across-the-Treatment-Journey-of-Uveal-Melanoma) **By year-end 2026** Start of IDE849 phase 3 registrational trial in extensive stage small cell lung cancer [Source](https://ir.ideayabio.com/2026-08-31-IDEAYA-Biosciences-Announces-Successful-FDA-Type-C-Meeting-for-IDE849,-DLL3-TOP1-ADC,-on-Phase-3-Registrational-Trial-Design-for-Potential-Accelerated-and-Full-Approval-in-Extensive-Stage-Small-Cell-Lung-Cancer) **Mid-2027** OptimUM-02 overall survival interim analysis [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) ## The money About $1.24 billion in cash, cash equivalents and marketable securities at June 30, 2026; runway guidance into 2030 unchanged. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) No product revenue. Collaboration revenue from Servier was $8.9 million in Q2 2026. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) ## Risks on the record - IDEAYA has not generated any revenue from product sales and reported an accumulated deficit of $947.5 million at June 30, 2026. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526332774/idya-20260630.htm) - Overall survival data from OptimUM-02 were immature at the January 2026 cutoff; an interim analysis is expected in mid-2027. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) - Analysts at GlobalData call the metastatic uveal melanoma market small and say long-term growth likely depends on earlier settings. [Source](https://www.clinicaltrialsarena.com/analyst-comment/asco-2026-darovasertib-metastatic-uveal-melanoma/) ## Questions investors ask ### What is aibio.space's Investor Rank for IDEAYA Biosciences? 9 out of 10, our most positive view. Darovasertib won a randomized trial, a filing is under way and cash runs into 2030; the small uveal melanoma market limits growth without the pipeline. This is opinion only, not a recommendation to buy, sell or hold, and it does not consider the share price or valuation. [Source](https://aibio.space/disclosures/#rank) ### What is darovasertib? Darovasertib is IDEAYA's oral PKC inhibitor for uveal melanoma, given with crizotinib in metastatic disease. In the randomized OptimUM-02 trial it achieved median progression-free survival of 6.9 months versus 3.1 months for investigator's choice. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) ### When will IDEAYA file for FDA approval of darovasertib? IDEAYA is submitting a new drug application under the FDA's real-time oncology review program. It expects to complete the submission in the second half of 2026. [Source](https://ir.ideayabio.com/2026-10-19-IDEAYA-Biosciences-and-Servier-Announce-Data-From-Three-Clinical-Trials-at-ESMO-2026-Supporting-the-Potential-of-Darovasertib-to-Become-a-Foundational-New-Therapy-for-Patients-Across-the-Treatment-Journey-of-Uveal-Melanoma) ### How much cash does IDEAYA Biosciences have? IDEAYA reported about $1.24 billion in cash, cash equivalents and marketable securities at June 30, 2026. It guides to cash runway into 2030. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) ### Who is the CEO of IDEAYA Biosciences? Yujiro S. Hata is president and CEO of IDEAYA. The board also elected him chairman effective June 16, 2026. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526279427/d39019d8k.htm) ### What is IDE849? IDE849 is a DLL3-targeting antibody drug conjugate with a TOP1 payload, partnered with Hengrui in China. After an FDA Type C meeting, IDEAYA plans a 400-patient phase 3 trial in previously treated extensive stage small cell lung cancer starting by year-end 2026. [Source](https://ir.ideayabio.com/2026-08-31-IDEAYA-Biosciences-Announces-Successful-FDA-Type-C-Meeting-for-IDE849,-DLL3-TOP1-ADC,-on-Phase-3-Registrational-Trial-Design-for-Potential-Accelerated-and-Full-Approval-in-Extensive-Stage-Small-Cell-Lung-Cancer) ### What is IDEAYA Biosciences's market cap? We do not publish live share prices. In its annual report, IDEAYA Biosciences, Inc. put the market value of shares held by non-affiliates (public float) at $1.80 billion as of Jun 30, 2025. Source ### Is IDEAYA Biosciences a smaller reporting company? SEC records list IDEAYA Biosciences, Inc.'s filer category as: Large accelerated filer. Source ### Where is IDEAYA Biosciences headquartered? SEC records list its business address as 5000 SHORELINE CT, SUITE 300, SOUTH SAN FRANCISCO, CA, 94080. Source ### When does IDEAYA Biosciences's fiscal year end? IDEAYA Biosciences, Inc.'s fiscal year ends on December 31, per SEC records. Source ### What did IDEAYA Biosciences last file with the SEC? Its most recent filing in our record is a 10-Q filed 2026-08-04. All of its filings are on SEC EDGAR. [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526332774/idya-20260630.htm) ### What industry is IDEAYA Biosciences in? Its SEC industry code (SIC 2834) is Pharmaceutical Preparations. Source ## Legal and investor matters Checked against IDEAYA Biosciences filings and press releases. Allegations are allegations; nothing here is a finding of fault. Reviewed Oct 25, 2026. Part II, Item 1 of the 10-Q filed 2026-08-04 states: "We are not currently a party to any litigation or legal proceedings that, in the opinion of our management, are likely to have a material adverse effect on our business." [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526332774/idya-20260630.htm) 1. 2026-06-16 Governance IDEAYA board elects Yujiro Hata chairman and Terry Rosen lead independent director IDEAYA reported that, effective 2026-06-16, its board elected Yujiro S. Hata as Chairman of the Board and Terry Rosen as Lead Independent Director. The 8-K is dated 2026-06-23 and was signed by Hata as President and Chief Executive Officer. [IDEAYA 8-K filed 2026-06-23](https://www.sec.gov/Archives/edgar/data/1676725/000119312526279427/d39019d8k.htm) 2. 2026-06-08 Financing IDEAYA prices offering of shares and pre-funded warrants at $27.00 IDEAYA entered an underwriting agreement on 2026-06-08 to sell 5,555,556 shares of common stock and pre-funded warrants for 5,555,576 shares, at a public price of $27.00 per share. The underwriters had a 30-day option to buy up to 1,666,669 additional shares. Underwriters agreed to buy the shares from the company at $25.38 per share. The 8-K was filed on 2026-06-10. [IDEAYA 8-K filed 2026-06-10](https://www.sec.gov/Archives/edgar/data/1676725/000119312526265833/d110954d8k.htm) 3. 2025-12-09 Other GSK gives notice to terminate IDEAYA collaboration, effective 2026-03-09 On 2025-12-09 GSK delivered formal written notice electing to terminate its 2020 Collaboration, Option and License Agreement with IDEAYA, effective 90 days later on 2026-03-09. GSK had communicated the decision on 2025-12-04. During the transition GSK will transfer the Werner Helicase (IDE275) and Pol Theta (IDE705) clinical programs to IDEAYA, which said its cash runway expectation into 2030 was unchanged. [IDEAYA 8-K filed 2025-12-12](https://www.sec.gov/Archives/edgar/data/1676725/000119312525317541/d800445d8k.htm) 4. 2025-08-29 Other IDEAYA licenses darovasertib ex-US to Servier for $210 million upfront On 2025-08-29 IDEAYA granted Servier an exclusive license to develop and commercialize darovasertib in all countries except the United States. Servier agreed to pay $210 million upfront, with eligibility for up to $100 million in development and regulatory milestones, up to $220 million in commercial milestones, and royalties on ex-US sales. IDEAYA said the payment extends its cash runway by at least twelve months. [IDEAYA 8-K filed 2025-09-02](https://www.sec.gov/Archives/edgar/data/1676725/000119312525193238/d800731d8k.htm) ## Pipeline | Program | Indication | Stage | |---|---|---| | Darovasertib + crizotinib | First-line HLA-A*02:01-negative metastatic uveal melanoma | Registrational phase 2/3 (OptimUM-02) met primary endpoint; NDA submission under RTOR, completion expected 2H 2026 [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) | | Darovasertib + crizotinib (OptimUM-11) | Adjuvant treatment of high-risk primary uveal melanoma | Phase 3, first patient dosed Sept. 2026 [Source](https://ir.ideayabio.com/2026-09-09-IDEAYA-Biosciences-and-Servier-Announce-First-Patient-Dosed-in-OptimUM-11-Global-Phase-3-Registrational-Trial-of-Darovasertib-and-Crizotinib-as-Adjuvant-Therapy-for-Subjects-with-Uveal-Melanoma) | | Darovasertib (OptimUM-09) | Neoadjuvant primary uveal melanoma | Phase 2 [Source](https://ir.ideayabio.com/2026-10-19-IDEAYA-Biosciences-and-Servier-Announce-Data-From-Three-Clinical-Trials-at-ESMO-2026-Supporting-the-Potential-of-Darovasertib-to-Become-a-Foundational-New-Therapy-for-Patients-Across-the-Treatment-Journey-of-Uveal-Melanoma) | | IDE849 (DLL3 TOP1 ADC) | Extensive stage small cell lung cancer, neuroendocrine carcinomas | Phase 1; phase 3 planned to start by year-end 2026 [Source](https://ir.ideayabio.com/2026-08-31-IDEAYA-Biosciences-Announces-Successful-FDA-Type-C-Meeting-for-IDE849,-DLL3-TOP1-ADC,-on-Phase-3-Registrational-Trial-Design-for-Potential-Accelerated-and-Full-Approval-in-Extensive-Stage-Small-Cell-Lung-Cancer) | | IDE892 (MTA-cooperative PRMT5 inhibitor) | MTAP-deleted solid tumors, including lung and pancreatic cancer | Phase 1/2, monotherapy expansion and combinations [Source](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-ex99_1.htm) | ## Stock chart Price chart and quote supplied by TradingView, delayed as the exchange requires. 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[Open NASDAQ:IDYA on TradingView](https://www.tradingview.com/symbols/NASDAQ-IDYA/). ## SEC filings and registration - **SEC name**: IDEAYA Biosciences, Inc. - **CIK**: 1676725 - **Industry (SIC)**: Pharmaceutical Preparations (2834) - **US tickers**: IDYA (Nasdaq) - **State or country of incorporation**: DE - **Fiscal year ends**: December 31 - **Filer category**: Large accelerated filer - **Business address**: 5000 SHORELINE CT, SUITE 300, SOUTH SAN FRANCISCO, CA, 94080 - **Phone**: 650-443-6209 - **Shares outstanding**: 96,489,484 as of 2026-07-31 (10-Q filed 2026-08-04) ### Recent filings (8-K and 6-K are the company's own announcements) - [10-Q](https://www.sec.gov/Archives/edgar/data/1676725/000119312526332774/idya-20260630.htm) filed 2026-08-04 - [8-K](https://www.sec.gov/Archives/edgar/data/1676725/000119312526331381/idya-20260804.htm) filed 2026-08-04 - [8-K](https://www.sec.gov/Archives/edgar/data/1676725/000119312526279427/d39019d8k.htm) filed 2026-06-23 - [8-K](https://www.sec.gov/Archives/edgar/data/1676725/000119312526265833/d110954d8k.htm) filed 2026-06-10 - [424B5](https://www.sec.gov/Archives/edgar/data/1676725/000119312526264032/d160204d424b5.htm) filed 2026-06-09 - [424B5](https://www.sec.gov/Archives/edgar/data/1676725/000119312526261756/d160204d424b5.htm) filed 2026-06-08 - [8-K](https://www.sec.gov/Archives/edgar/data/1676725/000119312526254476/d53214d8k.htm) filed 2026-06-03 - [8-K](https://www.sec.gov/Archives/edgar/data/1676725/000119312526251399/d138848d8k.htm) filed 2026-06-01 Source: [SEC EDGAR](https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0001676725), retrieved October 23, 2026. Shares outstanding is the cover-page figure from the latest periodic report. The SEC does not publish share prices. Who manages this page **This page is managed by aibio.space.** The company does not run, edit or pay for this page. News, desk views and Investor Ranks are written and managed independently by aibio.space under our editorial and analytical judgment. Opinion only, not investment advice. [How we work](https://aibio.space/disclosures/#paid) · [Terms](https://aibio.space/terms/#news) · [Request a correction](https://aibio.space/reputation/#update) --- Source page: https://aibio.space/companies/ideaya-biosciences/. Facts in aibio.space stories are checked against company filings and releases; opinion is labelled. Cite as: aibio.space, "IDEAYA Biosciences (IDYA): news, pipeline and catalysts", 2026-10-31, https://aibio.space/companies/ideaya-biosciences/